GLIOBLASTOMA. ASPECTS OF PATHOGENESIS AND THERAPEUTIC APPROACHES

Main Article Content

BON L.I.
LYCHKOVSKAYA M.A.

Abstract

Glioblastoma is considered one of the most aggressive malignant brain tumors, which has an extremely unfavorable prognosis and low patient survival. The low sensitivity to standard multimodal therapy is explained by the heterogeneity of the tumor cell pool and the presence of glioblastoma stem-like cells in the tumor. In recent years, much attention has been paid to the identification and study of molecular genetic disorders of glioblastoma. The most significant of them are the IDH1 gene mutation and the MGMT methylation status. Currently, the gold standard of treatment is the use of neuronavigation and intraoperative tumor fluorescence in surgery, these methods allow the most accurate and complete removal of the tumor. In this article, we will consider the pathogenesis, experimental technologies and modern methods of treating this disease.

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How to Cite
BON L.I., & LYCHKOVSKAYA M.A. (2022). GLIOBLASTOMA. ASPECTS OF PATHOGENESIS AND THERAPEUTIC APPROACHES. Innovat International Journal Of Medical & Pharmaceutical Sciences, 7(5), 1–6. Retrieved from https://www.innovatpublisher.com/index.php/iijmps/article/view/202
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Review Article(s)

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