FORMULATION DEVELOPMENT AND EVALUATION OF EMTRICITABINE PELLETS BY EXTRUSION SPHERONIZATION TECHNIQUE

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GADAKH PRAVIN
VIKRANT K NIKAM

Abstract

Pellets were prepared by extrusion spheronization technique. All the batches of pellets were spherical with good flowability and compressibility. Drug release from the pellets was affected by both % of lactose and % of drug load. % lactose showed positive effect on drug release from the pellets whereas % drug load showed negative effect on drug release from the pellets. Batch B12 was selected as best batch because it had lowest SSR (32.95) and the drug release at  2, 6 and 12 h were within the limits of desired drug release limits. The SEM study of optimized batch pellets showed that the pellets were spherical with compact surface.

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How to Cite
PRAVIN, G., & K NIKAM, V. (2021). FORMULATION DEVELOPMENT AND EVALUATION OF EMTRICITABINE PELLETS BY EXTRUSION SPHERONIZATION TECHNIQUE. Innovat International Journal Of Medical & Pharmaceutical Sciences, 6(1), 1–4. Retrieved from https://www.innovatpublisher.com/index.php/iijmps/article/view/117
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